Gaddam RR, Amalkar VS, Sali VK, Nakuluri K, Jacobs JS, Kim YR, Li Q, Bahal R, Irani K,* Vikram A.* Role of miR-204 in segmental cardiac effects of phenylephrine and pressure overload. Biochemical and Biophysical Research Communications. 2023 Jul 7;675:85-91. [PMID: 37454401] *Corresponding author.

Gaddam RR, Dhuri K, Kim YR, Jacobs JS, Kumar V, Li Q, Irani K, Bahal R,* and Vikram A.* g-peptide nucleic acid-based miR-122 inhibition rescues vascular endothelial dysfunction in mice fed a high-fat diet. Journal of Medicinal Chemistry. 2022 Feb 24;65(4):3332-3342. [PMID: 35133835, PMCID: PMC8883473] *Corresponding author.

Gaddam RR, Kim YR, Jacobs JS, Yoon JY, Li Q, Cai A, Shankaiahgari H, London B, Irani K, and Vikram A*. The microRNA-204-5p inhibits APJ signaling and confers resistance to cardiac hypertrophy and dysfunction. Clinical and Translational Medicine. 2022 Jan;12(1):e693. [PMID: 35060347] *Corresponding author.

Momin MY, Gaddam RR, Kravitz M, Gupta A, and Vikram A.* The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint. Cells. 2021. 9;10(11):3097. *Corresponding author. [PMID: 34831320].

Gaddam RR, Kim YR, Li Q, Jacobs JS, Gabani M, Mishra A, Promes JA, Imai Y, Irani K, Vikram A.* Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice. Biochemical and Biophysical Research Communications. 2020 Nov 5;532(2):167-172. [PMID: 32950230] *Corresponding author.

Gaddam RR, Jacobsen VP, Kim YR, Gabani M, Jacobs JS, Dhuri K, Kumar S, Kassan M, Li Q, Bahal R, Roghair R, Irani K, Vikram A.* Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice. Scientific Reports. 2020 Jun 22;10(1):10065. [PMID: 32572127] *Corresponding author.

Vikram A, Lewarchik CM, Yoon J, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim Y, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung S, Margulies KB, Kumar V, Bachschmid MM, London B & Irani K. (2017). Sirutin1 Regulates Cardiac Electrical Activity by Deacetylating the Cardiac Sodium Channel. Nature Medicine 23 361-367. DOI: 10.1038/nm.4284.

Vikram A, Kim Y, Kumar S, Li Q, Kassan M, Jacobs JS & Irani K. (2017). The Microbiome Remotely Promotes Endothelial Dysfunction Through Vascular MicroRNA-204-Mediated Downregulation of Sirtuin1. Nature Communications. (7) 12565. DOI: 10.1038/ncomms12565.

Tikoo K, Vikram A, Shrivastava S, Jena G, Shah H & Chhabra R. (2017). Parental High-Fat Diet Promotes Inflammatory  and Senescence-Related Changes in Prostate. Oxid Med Cell Longev (2017:4962950). PMID: 28261375. DOI: 10.1155/2017/4962950.

Vikram A, Jena G & Ramarao P. (2010). Pioglitazone Attenuates Prostatic Enlargement in Diet-Induced Insulin-Resistant Rats By Altering Lipid Distribution and Hyperinsulinaemia. British Journal of Pharmacology 161 (8) 1708-1721. DOI: 10.1111/j.1476-5381.2010.00994.x.

Vikram A, Jena GB, Ramarao P, Increased cell proliferation and contractility of the prostate gland in insulin-resistant rats: Linking hyperinsulinemia with prostatic hyperplasia. Prostate, 1 (2010) 79-89. [PMID: 19790233].

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